Serveur d'exploration sur la COVID chez les séniors

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Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic.

Identifieur interne : 000200 ( Main/Exploration ); précédent : 000199; suivant : 000201

Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic.

Auteurs : Adam S. Jasne [États-Unis] ; Pola Chojecka [États-Unis] ; Ilavarasy Maran [États-Unis] ; Razaz Mageid [États-Unis] ; Mohamed Eldokmak [États-Unis] ; Qiang Zhang [États-Unis] ; Karin Nystrom [États-Unis] ; Kelsey Vlieks [États-Unis] ; Michael Askenase [États-Unis] ; Nils Petersen [États-Unis] ; Guido J. Falcone [États-Unis] ; Charles R. Wira [États-Unis] ; Paul Lleva [États-Unis] ; Neer Zeevi [États-Unis] ; Reshma Narula [États-Unis] ; Hardik Amin [États-Unis] ; Dhasakumar Navaratnam [États-Unis] ; Caitlin Loomis [États-Unis] ; David Y. Hwang [États-Unis] ; Joseph Schindler [États-Unis] ; Ryan Hebert [États-Unis] ; Charles Matouk [États-Unis] ; Harlan M. Krumholz [États-Unis] ; Serena Spudich [États-Unis] ; Kevin N. Sheth [États-Unis] ; Lauren H. Sansing [États-Unis] ; Richa Sharma [États-Unis]

Source :

RBID : pubmed:32755347

Descripteurs français

English descriptors

Abstract

BACKGROUND

Anecdotal reports suggest fewer patients with stroke symptoms are presenting to hospitals during the coronavirus disease 2019 (COVID-19) pandemic. We quantify trends in stroke code calls and treatments at 3 Connecticut hospitals during the local emergence of COVID-19 and examine patient characteristics and stroke process measures at a Comprehensive Stroke Center (CSC) before and during the pandemic.

METHODS

Stroke code activity was analyzed from January 1 to April 28, 2020, and corresponding dates in 2019. Piecewise linear regression and spline models identified when stroke codes in 2020 began to decline and when they fell below 2019 levels. Patient-level data were analyzed in February versus March and April 2020 at the CSC to identify differences in patient characteristics during the pandemic.

RESULTS

A total of 822 stroke codes were activated at 3 hospitals from January 1 to April 28, 2020. The number of stroke codes/wk decreased by 12.8/wk from February 18 to March 16 (

CONCLUSIONS

Hospital presentation for stroke-like symptoms decreased during the COVID-19 pandemic, without differences in stroke severity or early outcomes. Individuals living outside of the CSC city were less likely to present for stroke codes at the CSC during the pandemic. Public health initiatives to increase awareness of presenting for non-COVID-19 medical emergencies such as stroke during the pandemic are critical.


DOI: 10.1161/STR.0000000000000347
PubMed: 32755347
PubMed Central: PMC7446978


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<country xml:lang="fr">États-Unis</country>
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</affiliation>
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<author>
<name sortKey="Eldokmak, Mohamed" sort="Eldokmak, Mohamed" uniqKey="Eldokmak M" first="Mohamed" last="Eldokmak">Mohamed Eldokmak</name>
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<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<region type="state">Connecticut</region>
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<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
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<author>
<name sortKey="Zhang, Qiang" sort="Zhang, Qiang" uniqKey="Zhang Q" first="Qiang" last="Zhang">Qiang Zhang</name>
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<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Nystrom, Karin" sort="Nystrom, Karin" uniqKey="Nystrom K" first="Karin" last="Nystrom">Karin Nystrom</name>
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<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Vlieks, Kelsey" sort="Vlieks, Kelsey" uniqKey="Vlieks K" first="Kelsey" last="Vlieks">Kelsey Vlieks</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Askenase, Michael" sort="Askenase, Michael" uniqKey="Askenase M" first="Michael" last="Askenase">Michael Askenase</name>
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<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Petersen, Nils" sort="Petersen, Nils" uniqKey="Petersen N" first="Nils" last="Petersen">Nils Petersen</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Falcone, Guido J" sort="Falcone, Guido J" uniqKey="Falcone G" first="Guido J" last="Falcone">Guido J. Falcone</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Wira, Charles R" sort="Wira, Charles R" uniqKey="Wira C" first="Charles R" last="Wira">Charles R. Wira</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Emergency Medicine (C.R.W.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Emergency Medicine (C.R.W.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Lleva, Paul" sort="Lleva, Paul" uniqKey="Lleva P" first="Paul" last="Lleva">Paul Lleva</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Zeevi, Neer" sort="Zeevi, Neer" uniqKey="Zeevi N" first="Neer" last="Zeevi">Neer Zeevi</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Narula, Reshma" sort="Narula, Reshma" uniqKey="Narula R" first="Reshma" last="Narula">Reshma Narula</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Amin, Hardik" sort="Amin, Hardik" uniqKey="Amin H" first="Hardik" last="Amin">Hardik Amin</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Navaratnam, Dhasakumar" sort="Navaratnam, Dhasakumar" uniqKey="Navaratnam D" first="Dhasakumar" last="Navaratnam">Dhasakumar Navaratnam</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Loomis, Caitlin" sort="Loomis, Caitlin" uniqKey="Loomis C" first="Caitlin" last="Loomis">Caitlin Loomis</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hwang, David Y" sort="Hwang, David Y" uniqKey="Hwang D" first="David Y" last="Hwang">David Y. Hwang</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Schindler, Joseph" sort="Schindler, Joseph" uniqKey="Schindler J" first="Joseph" last="Schindler">Joseph Schindler</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hebert, Ryan" sort="Hebert, Ryan" uniqKey="Hebert R" first="Ryan" last="Hebert">Ryan Hebert</name>
<affiliation wicri:level="2">
<nlm:affiliation>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Matouk, Charles" sort="Matouk, Charles" uniqKey="Matouk C" first="Charles" last="Matouk">Charles Matouk</name>
<affiliation wicri:level="2">
<nlm:affiliation>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Krumholz, Harlan M" sort="Krumholz, Harlan M" uniqKey="Krumholz H" first="Harlan M" last="Krumholz">Harlan M. Krumholz</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Cardiology (H.M.K.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Cardiology (H.M.K.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Spudich, Serena" sort="Spudich, Serena" uniqKey="Spudich S" first="Serena" last="Spudich">Serena Spudich</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Sheth, Kevin N" sort="Sheth, Kevin N" uniqKey="Sheth K" first="Kevin N" last="Sheth">Kevin N. Sheth</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Sansing, Lauren H" sort="Sansing, Lauren H" uniqKey="Sansing L" first="Lauren H" last="Sansing">Lauren H. Sansing</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Sharma, Richa" sort="Sharma, Richa" uniqKey="Sharma R" first="Richa" last="Sharma">Richa Sharma</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32755347</idno>
<idno type="pmid">32755347</idno>
<idno type="doi">10.1161/STR.0000000000000347</idno>
<idno type="pmc">PMC7446978</idno>
<idno type="wicri:Area/Main/Corpus">000823</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000823</idno>
<idno type="wicri:Area/Main/Curation">000823</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000823</idno>
<idno type="wicri:Area/Main/Exploration">000823</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic.</title>
<author>
<name sortKey="Jasne, Adam S" sort="Jasne, Adam S" uniqKey="Jasne A" first="Adam S" last="Jasne">Adam S. Jasne</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Chojecka, Pola" sort="Chojecka, Pola" uniqKey="Chojecka P" first="Pola" last="Chojecka">Pola Chojecka</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Maran, Ilavarasy" sort="Maran, Ilavarasy" uniqKey="Maran I" first="Ilavarasy" last="Maran">Ilavarasy Maran</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Mageid, Razaz" sort="Mageid, Razaz" uniqKey="Mageid R" first="Razaz" last="Mageid">Razaz Mageid</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Eldokmak, Mohamed" sort="Eldokmak, Mohamed" uniqKey="Eldokmak M" first="Mohamed" last="Eldokmak">Mohamed Eldokmak</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Zhang, Qiang" sort="Zhang, Qiang" uniqKey="Zhang Q" first="Qiang" last="Zhang">Qiang Zhang</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Nystrom, Karin" sort="Nystrom, Karin" uniqKey="Nystrom K" first="Karin" last="Nystrom">Karin Nystrom</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Vlieks, Kelsey" sort="Vlieks, Kelsey" uniqKey="Vlieks K" first="Kelsey" last="Vlieks">Kelsey Vlieks</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Askenase, Michael" sort="Askenase, Michael" uniqKey="Askenase M" first="Michael" last="Askenase">Michael Askenase</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Petersen, Nils" sort="Petersen, Nils" uniqKey="Petersen N" first="Nils" last="Petersen">Nils Petersen</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Falcone, Guido J" sort="Falcone, Guido J" uniqKey="Falcone G" first="Guido J" last="Falcone">Guido J. Falcone</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Wira, Charles R" sort="Wira, Charles R" uniqKey="Wira C" first="Charles R" last="Wira">Charles R. Wira</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Emergency Medicine (C.R.W.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Emergency Medicine (C.R.W.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Lleva, Paul" sort="Lleva, Paul" uniqKey="Lleva P" first="Paul" last="Lleva">Paul Lleva</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Zeevi, Neer" sort="Zeevi, Neer" uniqKey="Zeevi N" first="Neer" last="Zeevi">Neer Zeevi</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Narula, Reshma" sort="Narula, Reshma" uniqKey="Narula R" first="Reshma" last="Narula">Reshma Narula</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Amin, Hardik" sort="Amin, Hardik" uniqKey="Amin H" first="Hardik" last="Amin">Hardik Amin</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Navaratnam, Dhasakumar" sort="Navaratnam, Dhasakumar" uniqKey="Navaratnam D" first="Dhasakumar" last="Navaratnam">Dhasakumar Navaratnam</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Loomis, Caitlin" sort="Loomis, Caitlin" uniqKey="Loomis C" first="Caitlin" last="Loomis">Caitlin Loomis</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hwang, David Y" sort="Hwang, David Y" uniqKey="Hwang D" first="David Y" last="Hwang">David Y. Hwang</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Schindler, Joseph" sort="Schindler, Joseph" uniqKey="Schindler J" first="Joseph" last="Schindler">Joseph Schindler</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hebert, Ryan" sort="Hebert, Ryan" uniqKey="Hebert R" first="Ryan" last="Hebert">Ryan Hebert</name>
<affiliation wicri:level="2">
<nlm:affiliation>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Matouk, Charles" sort="Matouk, Charles" uniqKey="Matouk C" first="Charles" last="Matouk">Charles Matouk</name>
<affiliation wicri:level="2">
<nlm:affiliation>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Krumholz, Harlan M" sort="Krumholz, Harlan M" uniqKey="Krumholz H" first="Harlan M" last="Krumholz">Harlan M. Krumholz</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Cardiology (H.M.K.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Cardiology (H.M.K.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Spudich, Serena" sort="Spudich, Serena" uniqKey="Spudich S" first="Serena" last="Spudich">Serena Spudich</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Sheth, Kevin N" sort="Sheth, Kevin N" uniqKey="Sheth K" first="Kevin N" last="Sheth">Kevin N. Sheth</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Sansing, Lauren H" sort="Sansing, Lauren H" uniqKey="Sansing L" first="Lauren H" last="Sansing">Lauren H. Sansing</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Sharma, Richa" sort="Sharma, Richa" uniqKey="Sharma R" first="Richa" last="Sharma">Richa Sharma</name>
<affiliation wicri:level="2">
<nlm:affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Connecticut</region>
</placeName>
<wicri:cityArea>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Stroke</title>
<idno type="eISSN">1524-4628</idno>
<imprint>
<date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Brain Ischemia (diagnosis)</term>
<term>Brain Ischemia (epidemiology)</term>
<term>Brain Ischemia (physiopathology)</term>
<term>Brain Ischemia (therapy)</term>
<term>Cohort Studies (MeSH)</term>
<term>Comorbidity (MeSH)</term>
<term>Connecticut (epidemiology)</term>
<term>Coronary Artery Disease (epidemiology)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Dyslipidemias (epidemiology)</term>
<term>Emergency Medical Services (MeSH)</term>
<term>Ethnic Groups (MeSH)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Hypertension (epidemiology)</term>
<term>Income (MeSH)</term>
<term>Insurance, Health (MeSH)</term>
<term>Intracranial Hemorrhages (diagnosis)</term>
<term>Intracranial Hemorrhages (epidemiology)</term>
<term>Intracranial Hemorrhages (physiopathology)</term>
<term>Intracranial Hemorrhages (therapy)</term>
<term>Male (MeSH)</term>
<term>Medically Uninsured (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Outcome and Process Assessment, Health Care (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Severity of Illness Index (MeSH)</term>
<term>Stroke (diagnosis)</term>
<term>Stroke (epidemiology)</term>
<term>Stroke (physiopathology)</term>
<term>Stroke (therapy)</term>
<term>Substance-Related Disorders (epidemiology)</term>
<term>Telemedicine (MeSH)</term>
<term>Thrombectomy (MeSH)</term>
<term>Thrombolytic Therapy (MeSH)</term>
<term>Time-to-Treatment (statistics & numerical data)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Accident vasculaire cérébral (diagnostic)</term>
<term>Accident vasculaire cérébral (physiopathologie)</term>
<term>Accident vasculaire cérébral (thérapie)</term>
<term>Accident vasculaire cérébral (épidémiologie)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Assurance maladie (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Comorbidité (MeSH)</term>
<term>Connecticut (épidémiologie)</term>
<term>Dyslipidémies (épidémiologie)</term>
<term>Délai jusqu'au traitement (statistiques et données numériques)</term>
<term>Encéphalopathie ischémique (diagnostic)</term>
<term>Encéphalopathie ischémique (physiopathologie)</term>
<term>Encéphalopathie ischémique (thérapie)</term>
<term>Encéphalopathie ischémique (épidémiologie)</term>
<term>Ethnies (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Hypertension artérielle (épidémiologie)</term>
<term>Hémorragies intracrâniennes (diagnostic)</term>
<term>Hémorragies intracrâniennes (physiopathologie)</term>
<term>Hémorragies intracrâniennes (thérapie)</term>
<term>Hémorragies intracrâniennes (épidémiologie)</term>
<term>Indice de gravité de la maladie (MeSH)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Maladie des artères coronaires (épidémiologie)</term>
<term>Mâle (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Personnes sans assurance médicale (MeSH)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Revenu (MeSH)</term>
<term>Services des urgences médicales (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Thrombectomie (MeSH)</term>
<term>Traitement thrombolytique (MeSH)</term>
<term>Troubles liés à une substance (épidémiologie)</term>
<term>Télémédecine (MeSH)</term>
<term>Études de cohortes (MeSH)</term>
<term>Études rétrospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en">
<term>Connecticut</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Brain Ischemia</term>
<term>Intracranial Hemorrhages</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Encéphalopathie ischémique</term>
<term>Hémorragies intracrâniennes</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Brain Ischemia</term>
<term>Coronary Artery Disease</term>
<term>Coronavirus Infections</term>
<term>Dyslipidemias</term>
<term>Hypertension</term>
<term>Intracranial Hemorrhages</term>
<term>Pneumonia, Viral</term>
<term>Stroke</term>
<term>Substance-Related Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Encéphalopathie ischémique</term>
<term>Hémorragies intracrâniennes</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Brain Ischemia</term>
<term>Intracranial Hemorrhages</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en">
<term>Time-to-Treatment</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr">
<term>Délai jusqu'au traitement</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Brain Ischemia</term>
<term>Intracranial Hemorrhages</term>
<term>Stroke</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Encéphalopathie ischémique</term>
<term>Hémorragies intracrâniennes</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Accident vasculaire cérébral</term>
<term>Connecticut</term>
<term>Dyslipidémies</term>
<term>Encéphalopathie ischémique</term>
<term>Hypertension artérielle</term>
<term>Hémorragies intracrâniennes</term>
<term>Infections à coronavirus</term>
<term>Maladie des artères coronaires</term>
<term>Pneumopathie virale</term>
<term>Troubles liés à une substance</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Betacoronavirus</term>
<term>Cohort Studies</term>
<term>Comorbidity</term>
<term>Emergency Medical Services</term>
<term>Ethnic Groups</term>
<term>Female</term>
<term>Humans</term>
<term>Income</term>
<term>Insurance, Health</term>
<term>Male</term>
<term>Medically Uninsured</term>
<term>Middle Aged</term>
<term>Outcome and Process Assessment, Health Care</term>
<term>Pandemics</term>
<term>Retrospective Studies</term>
<term>Severity of Illness Index</term>
<term>Telemedicine</term>
<term>Thrombectomy</term>
<term>Thrombolytic Therapy</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Assurance maladie</term>
<term>Betacoronavirus</term>
<term>Comorbidité</term>
<term>Ethnies</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de gravité de la maladie</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Personnes sans assurance médicale</term>
<term>Revenu</term>
<term>Services des urgences médicales</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Thrombectomie</term>
<term>Traitement thrombolytique</term>
<term>Télémédecine</term>
<term>Études de cohortes</term>
<term>Études rétrospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>
<b>BACKGROUND</b>
</p>
<p>Anecdotal reports suggest fewer patients with stroke symptoms are presenting to hospitals during the coronavirus disease 2019 (COVID-19) pandemic. We quantify trends in stroke code calls and treatments at 3 Connecticut hospitals during the local emergence of COVID-19 and examine patient characteristics and stroke process measures at a Comprehensive Stroke Center (CSC) before and during the pandemic.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
</p>
<p>Stroke code activity was analyzed from January 1 to April 28, 2020, and corresponding dates in 2019. Piecewise linear regression and spline models identified when stroke codes in 2020 began to decline and when they fell below 2019 levels. Patient-level data were analyzed in February versus March and April 2020 at the CSC to identify differences in patient characteristics during the pandemic.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>RESULTS</b>
</p>
<p>A total of 822 stroke codes were activated at 3 hospitals from January 1 to April 28, 2020. The number of stroke codes/wk decreased by 12.8/wk from February 18 to March 16 (</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSIONS</b>
</p>
<p>Hospital presentation for stroke-like symptoms decreased during the COVID-19 pandemic, without differences in stroke severity or early outcomes. Individuals living outside of the CSC city were less likely to present for stroke codes at the CSC during the pandemic. Public health initiatives to increase awareness of presenting for non-COVID-19 medical emergencies such as stroke during the pandemic are critical.</p>
</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">32755347</PMID>
<DateCompleted>
<Year>2020</Year>
<Month>09</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised>
<Year>2020</Year>
<Month>09</Month>
<Day>11</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1524-4628</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>51</Volume>
<Issue>9</Issue>
<PubDate>
<Year>2020</Year>
<Month>09</Month>
</PubDate>
</JournalIssue>
<Title>Stroke</Title>
<ISOAbbreviation>Stroke</ISOAbbreviation>
</Journal>
<ArticleTitle>Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic.</ArticleTitle>
<Pagination>
<MedlinePgn>2664-2673</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1161/STR.0000000000000347</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND">Anecdotal reports suggest fewer patients with stroke symptoms are presenting to hospitals during the coronavirus disease 2019 (COVID-19) pandemic. We quantify trends in stroke code calls and treatments at 3 Connecticut hospitals during the local emergence of COVID-19 and examine patient characteristics and stroke process measures at a Comprehensive Stroke Center (CSC) before and during the pandemic.</AbstractText>
<AbstractText Label="METHODS">Stroke code activity was analyzed from January 1 to April 28, 2020, and corresponding dates in 2019. Piecewise linear regression and spline models identified when stroke codes in 2020 began to decline and when they fell below 2019 levels. Patient-level data were analyzed in February versus March and April 2020 at the CSC to identify differences in patient characteristics during the pandemic.</AbstractText>
<AbstractText Label="RESULTS">A total of 822 stroke codes were activated at 3 hospitals from January 1 to April 28, 2020. The number of stroke codes/wk decreased by 12.8/wk from February 18 to March 16 (
<i>P</i>
=0.0360) with nadir of 39.6% of expected stroke codes called from March 10 to 16 (30% decrease in total stroke codes during the pandemic weeks in 2020 versus 2019). There was no commensurate increase in within-network telestroke utilization. Compared with before the pandemic (n=167), pandemic-epoch stroke code patients at the CSC (n=211) were more likely to have histories of hypertension, dyslipidemia, coronary artery disease, and substance abuse; no or public health insurance; lower median household income; and to live in the CSC city (
<i>P</i>
<0.05). There was no difference in age, sex, race/ethnicity, stroke severity, time to presentation, door-to-needle/door-to-reperfusion times, or discharge modified Rankin Scale.</AbstractText>
<AbstractText Label="CONCLUSIONS">Hospital presentation for stroke-like symptoms decreased during the COVID-19 pandemic, without differences in stroke severity or early outcomes. Individuals living outside of the CSC city were less likely to present for stroke codes at the CSC during the pandemic. Public health initiatives to increase awareness of presenting for non-COVID-19 medical emergencies such as stroke during the pandemic are critical.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Jasne</LastName>
<ForeName>Adam S</ForeName>
<Initials>AS</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Chojecka</LastName>
<ForeName>Pola</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Maran</LastName>
<ForeName>Ilavarasy</ForeName>
<Initials>I</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Mageid</LastName>
<ForeName>Razaz</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Eldokmak</LastName>
<ForeName>Mohamed</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Zhang</LastName>
<ForeName>Qiang</ForeName>
<Initials>Q</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Nystrom</LastName>
<ForeName>Karin</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Vlieks</LastName>
<ForeName>Kelsey</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Askenase</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Petersen</LastName>
<ForeName>Nils</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Falcone</LastName>
<ForeName>Guido J</ForeName>
<Initials>GJ</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Wira</LastName>
<ForeName>Charles R</ForeName>
<Initials>CR</Initials>
<Suffix>3rd</Suffix>
<AffiliationInfo>
<Affiliation>Department of Emergency Medicine (C.R.W.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Lleva</LastName>
<ForeName>Paul</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Zeevi</LastName>
<ForeName>Neer</ForeName>
<Initials>N</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Narula</LastName>
<ForeName>Reshma</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Amin</LastName>
<ForeName>Hardik</ForeName>
<Initials>H</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Navaratnam</LastName>
<ForeName>Dhasakumar</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Loomis</LastName>
<ForeName>Caitlin</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hwang</LastName>
<ForeName>David Y</ForeName>
<Initials>DY</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Schindler</LastName>
<ForeName>Joseph</ForeName>
<Initials>J</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hebert</LastName>
<ForeName>Ryan</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Matouk</LastName>
<ForeName>Charles</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Departments of Neurosurgery and of Radiology and Biomedical Imaging (R.H., C.M.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Krumholz</LastName>
<ForeName>Harlan M</ForeName>
<Initials>HM</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology (H.M.K.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Spudich</LastName>
<ForeName>Serena</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sheth</LastName>
<ForeName>Kevin N</ForeName>
<Initials>KN</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sansing</LastName>
<ForeName>Lauren H</ForeName>
<Initials>LH</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sharma</LastName>
<ForeName>Richa</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Department of Neurology (A.S.J., P.C., I.M., R.M., M.E., Q.Z., K.N., K.V., M.A., N.P., G.J.F., P.L., N.Z., R.N., H.A., D.N., C.L., D.Y.H., J.S., S.S., K.N.S., L.H.S., R.S.), Yale University School of Medicine, New Haven, CT.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y">
<Grant>
<GrantID>R01 NR018335</GrantID>
<Acronym>NR</Acronym>
<Agency>NINR NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant>
<GrantID>U24 NS107136</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant>
<GrantID>R03 NS112859</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant>
<GrantID>U24 NS107215</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant>
<GrantID>U01 NS106513</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant>
<GrantID>R01 NS110721</GrantID>
<Acronym>NS</Acronym>
<Agency>NINDS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic">
<Year>2020</Year>
<Month>07</Month>
<Day>31</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo>
<Country>United States</Country>
<MedlineTA>Stroke</MedlineTA>
<NlmUniqueID>0235266</NlmUniqueID>
<ISSNLinking>0039-2499</ISSNLinking>
</MedlineJournalInfo>
<SupplMeshList>
<SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList>
<CommentsCorrections RefType="CommentIn">
<RefSource>Stroke. 2020 Sep;51(9):2613-2614</RefSource>
<PMID Version="1">32755344</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002545" MajorTopicYN="N">Brain Ischemia</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D003237" MajorTopicYN="N" Type="Geographic">Connecticut</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D003324" MajorTopicYN="N">Coronary Artery Disease</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D050171" MajorTopicYN="N">Dyslipidemias</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D004632" MajorTopicYN="N">Emergency Medical Services</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005006" MajorTopicYN="N">Ethnic Groups</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006973" MajorTopicYN="N">Hypertension</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007182" MajorTopicYN="N">Income</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007348" MajorTopicYN="N">Insurance, Health</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D020300" MajorTopicYN="N">Intracranial Hemorrhages</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017057" MajorTopicYN="N">Medically Uninsured</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D010043" MajorTopicYN="N">Outcome and Process Assessment, Health Care</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D020521" MajorTopicYN="N">Stroke</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D019966" MajorTopicYN="N">Substance-Related Disorders</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017216" MajorTopicYN="N">Telemedicine</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D017131" MajorTopicYN="N">Thrombectomy</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015912" MajorTopicYN="N">Thrombolytic Therapy</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D061665" MajorTopicYN="N">Time-to-Treatment</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="Y">coronavirus disease</Keyword>
<Keyword MajorTopicYN="Y">pandemics</Keyword>
<Keyword MajorTopicYN="Y">stroke</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="pubmed">
<Year>2020</Year>
<Month>8</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
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